Multiple Sclerosis Essay Research Paper The Inside

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Multiple Sclerosis Essay, Research Paper

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The Inside Disease

Multiple Sclerosis affects 350,000 people around the United States. Judy Rhamini, a forty- six-year-old female parent of two, was diagnosed with the stultifying disease in 1988. In late 1997, her onslaughts had become so annihilating that one of them left her weaponries and legs temporarily paralyzed. To battle the onslaughts, Mrs. Rhamini began a four- hr day-to-day regimen of endovenous steroids. Within hebdomads, her hurting was gone. Judy Rhamini now takes Avonex, which is a beta- interferon, and since get downing this intervention, she has merely had two mild onslaughts. With progresss in the medical field, there is now hope that a remedy for multiple induration will be found in the close hereafter.

Many new drugs are being developed to stunt the patterned advance of multiple induration. Some of these new drugs are being used today, and they are assisting patients cope with the adversities of multiple induration. Judy Rhamini tells how Avonex has helped her ; & # 8220 ; My MS has decidedly slowed down. I am so grateful. & # 8221 ; However, to happen a remedy, scientists still have to come to a distinguishable decision to what causes this disease. The lone manner to free a patient of this atrocious disease is to assail the chief perpetrator responsible for conveying the disease upon a individual.

Although scientists are non wholly certain, there are many possibilities as to what causes multiple induration. Scientists feel that there are two chief possible causes for multiple induration: the environment in which a individual lives, and Herpes Virus 6. Experts are non wholly certain, but they are working out the jobs, and are confident they will happen the reply shortly. Some viruses have been thought to be a cause, but it normally comes down to the environment in which a individual lives.

Guesss have been made that the environment in which a individual lives, may be a cause for multiple induration. There are about 350,000 Americans with MS, and estimates suggest that there are two hundred new instances diagnosed each hebdomad. With this in head, it would do a individual think that America is the environment to fault, and this merely might be the instance. Research workers have found that the farther one lives from the equator, the more likely one is to develop multiple induration. Obviously, there has to be more causes for multiple induration. There is no manner one can develop a disease entirely by populating in a certain country. In add-on to the environment, viruses common in the country may besides convey on this disease.

In the past, many viruses have been linked to multiple induration. The latest and strongest instance has been Herpes Virus 6 ( HHV-6 ) . In a recent survey, more than 70 per centum of the patients tested showed marks of active infections of HHV-6. This made scientists and physicians feel as if they had found the cause, but they still did non hold the 100 per centum certain consequences they needed. The cause is still unknown, because HHV-6 may merely be a symptom of multiple induration. Multiple induration has many symptoms, and scientists fear that their latest find may merely be that, an unfortunate symptom that patients will hold to endure with.

Multiple induration is non an easy disease to set a finger on. Patients are frequently misdiagnosed, and are forced to get by with their symptoms until they are eventually diagnosed right. Multiple induration has many symptoms, some physical and some mental. The physical symptoms may be more hard of the two to cover with.

Multiple induration can be diagnosed with the happening of many physical symptoms. Some enfeebling physical symptoms of multiple induration can be change in vision, unnatural esthesiss throughout the organic structure, and musculus failing. Symptoms appear to patients in onslaughts and / or stages. Symptoms can look and vanish in a affair of yearss or hebdomads. Many of the chief physical symptoms go into remittal for some clip, but many may be lasting. Remember, most patients become paralytic as the disease progresses. Along with physical symptoms, multiple induration can convey on many mental alterations to a individual.

Multiple induration brings on many jobs to the mental capablenesss of a patient. Multiple induration can coerce a individual to travel through psychological alterations that can be lay waste toing to a individual & # 8217 ; s life. These alterations can wholly change a patient & # 8217 ; s personality, thereby doing jobs throughout even a patient & # 8217 ; s household. These alterations and cognitive damages can do a household feel as if they do non even know their loved one any longer. These symptoms may be seen from the outside, but the existent harm is taking topographic point inside a patient & # 8217 ; s organic structure and head. These annihilating effects are adequate to do any individual & # 8217 ; s jaw bead.

The harmful effects multiple induration has on a patient can be devolving and irreversible. Multiple induration can rupture a household apart, merely as the manner the disease destroys a patient & # 8217 ; s organic structure. The disease is a hardhearted machine that will oppress anything that gets in its manner. The immune system is normally the first victim of the wrath of this dismaying disease.

Multiple induration is a disease that deteriorates a patient & # 8217 ; s muscular and immune systems. Multiple induration is an auto-immune disease where cells use their arms against the medulla sheath, T-cells that protect our immune system, and destruct them. Effectss like this leave 30 per centum of victims bound to a wheelchair after contending the disease for 20 old ages. In add-on to damaging the physical facets of a individual & # 8217 ; s life, multiple induration besides attacks a patient & # 8217 ; s encephalon. The disease really severs nerve fibres in the encephalon, and that causes irreversible harm. This harm may do a patient memory loss, the loss of cognitive accomplishments, and even alter a patient & # 8217 ; s personality. With these mental and physical alterations, a patient & # 8217 ; s normal household life may be changed around, and jobs may be caused.

Multiple induration can set many unwanted force per unit areas on household life. A patient fighting with MS may meet many psychological alterations. These alterations may change the patient & # 8217 ; s memory, and his or her attitude towards the remainder of one & # 8217 ; s household. These fluctuations may do a household feel as if they do non even know their loved one anymore. Multiple induration can besides set emphasis on a matrimony. The partner of a patient may get down to experience as if he or she were & # 8220 ; being on call & # 8221 ; , or the MS patient may experience as if he or she were & # 8220 ; being a bother. & # 8221 ; These effects can set a strain on a twosome & # 8217 ; s normal emotional life. This disease may besides set a strain on a household & # 8217 ; s fiscal state of affairs besides. With the mean one-year cost for services and drugs being between $ 20,000 to $ 25,000, the monetary values of attention taking can set a immense damper on a household & # 8217 ; s chequebook. Medicines can account for approximately half of that cost, with the mean one-year cost for medicines being around $ 10,000. Yttrium

et the monetary values for medicines will still increase with the development of new drugs.

Although a remedy has non been found for multiple induration, research workers are developing new drugs to handle the disease each and every twenty-four hours. Traditional drugs have been around for a long clip, but all they do is set a damper on some symptoms for a short period of clip. The new drugs being developed are made in hopes of bring arounding multiple induration, and many of these have a great affect on the organic structure. The most affectional drugs out on the market now are beta-interferons.

Beta-interferons are the newest general type of drugs being produced to handle multiple induration. If beta-interferons, such as Avonex, are used really early in diagnosing, so patients may make better. The likeliness of halting the disease becomes less and lesser as clip goes on. However, with the aid of Avonex, the gradual loss of encephalon tissue can be prevented. Avonex has besides been proven to decelerate the shrinking of encephalon tissue, hence, lengthening a patient & # 8217 ; s clip of maintaining his or her mental abilities strong. In add-on to Avonex, other beta-interferons have been produced. Three of these drugs are Novantrone, Baclofen, and Copaxine. All three of these drugs have been shown to modestly cut down the figure and badness of MS symptoms. These drugs have been applied to patients, and have been found to hold minimum side effects. Other drugs have been produced, and would be placed on the market if it were non due to their harmful side effects.

Beta-interferons have been found to hold minimum side effects such as icinesss and redness of the injection site. Other more productive drugs have been developed that may non be used because they tend to make more injury than they do good. Two illustrations of drugs like these are Cyclosporine and Prednisone. Prednisone has been found to cut down the badness of MS tantrums in patients, but brings upon acne, diabetes, high blood pressure, and even mood swings. Cyclosporine has besides been proved to significantly decelerate the patterned advance of neurological upset, but its side effects are excessively toxic to make patients any good. Although these drugs still have some jobs, scientists are headed in the right way. With all the good these drugs can make, it is merely a affair of clip before a medicine is found that will bring around multiple induration.

Although Multiple Sclerosis is a degenerative disease, there is visible radiation at the terminal of the tunnel. Technology has progressed so much over the old ages that there have been so many new finds about the disease. Now, when a individual is diagnosed, there is hope. With the progresss in the medical field, and with the achievements of the drugs that are being produced, there is hope for a remedy. Suzanne Arens, a 39 twelvemonth old adult female who was late diagnosed, leaves on this note: & # 8220 ; I used to see a wheelchair at the terminal of the tunnel, now I see a life. & # 8221 ; With attitudes like this, people waiting for a remedy will acquire what they deserve when the physicians do develop the manner to alleviate them of their agony.

Berardelli, Phil. & # 8220 ; Biomedicine: Herpes Virus Linked to Multiple Sclerosis. & # 8221 ; Science, 5

December 1997. Electric Library. Online. Internet. 21 January 2000.

Haney, Daniel Q. & # 8220 ; Multiple Sclerosis Study Released. & # 8221 ; Register-Guard, 28 January 1998.

Reproduced in SIRS Researcher CD-ROM, SIRS Mandarin. Fall 1999.

Kalb, Rosalind C. Multiple Sclerosis: A Guide for Families. New York: Dema

Vermonde, 1998

& # 8220 ; Multiple Sclerosis Research Update. & # 8221 ; Rehab Brief, 5 November 1994, 1-4. Reproduced

in SIRS Researcher CD-ROM, SIRS Government Reporter. Fall 1999.

& # 8220 ; Multiple Sclerosis. & # 8221 ; Harvard Women & # 8217 ; s Health Watch, February 1998, 4-5. Reproduced

in SIRS Researcher CD-ROM, SIRS Mandarin. Fall 1999.

Nash, J. Madaline. & # 8220 ; Medicine: Contending a Crippler a New Drug Appears to be the First to

Decelerate the Progress of Multiple Sclerosis. & # 8221 ; Time, 29 March 1993. Electric Library.

Online. Internet. 20 January 2000.

Rowen, Carol. & # 8220 ; Multiple Sclerosis: Hope Through Research. & # 8221 ; Multiple Sclerosis: Hope

Through Research, September 1996, 1-44. Reproduced in SIRS Researcher

CD-ROM, SIRS Government Reporter. Fall 1999.

Siegel, Judy. & # 8220 ; Hope Finds its Way to the Marketplace. & # 8221 ; Jerusalem Post, 16 October 1996,

Page 6. Electric Library. Online. Internet. 25 January 2000.

Squires, Sally. & # 8220 ; Interferon Drugs Offer Hope to MS Patients ; Researchers Say Injections

Reduce the Brain Shrinking that is Common in Patients. & # 8221 ; The Washington Post,

4 May 1999. Electric Library. Online. Internet. 20 January 2000.

Talan, Jaime. & # 8220 ; New Hope for MS Patients. & # 8221 ; The Record, 26 January 1998. Reproduced

In SIRS Researcher CD-ROM, SIRS Mandarin. Fall 1999.

Bibliography

Berardelli, Phil. & # 8220 ; Biomedicine: Herpes Virus Linked to Multiple Sclerosis. & # 8221 ; Science, 5

December 1997. Electric Library. Online. Internet. 21 January 2000.

Haney, Daniel Q. & # 8220 ; Multiple Sclerosis Study Released. & # 8221 ; Register-Guard, 28 January 1998.

Reproduced in SIRS Researcher CD-ROM, SIRS Mandarin. Fall 1999.

Kalb, Rosalind C. Multiple Sclerosis: A Guide for Families. New York: Dema

Vermonde, 1998

& # 8220 ; Multiple Sclerosis Research Update. & # 8221 ; Rehab Brief, 5 November 1994, 1-4. Reproduced

in SIRS Researcher CD-ROM, SIRS Government Reporter. Fall 1999.

& # 8220 ; Multiple Sclerosis. & # 8221 ; Harvard Women & # 8217 ; s Health Watch, February 1998, 4-5. Reproduced

in SIRS Researcher CD-ROM, SIRS Mandarin. Fall 1999.

Nash, J. Madaline. & # 8220 ; Medicine: Contending a Crippler a New Drug Appears to be the First to

Decelerate the Progress of Multiple Sclerosis. & # 8221 ; Time, 29 March 1993. Electric Library.

Online. Internet. 20 January 2000.

Rowen, Carol. & # 8220 ; Multiple Sclerosis: Hope Through Research. & # 8221 ; Multiple Sclerosis: Hope

Through Research, September 1996, 1-44. Reproduced in SIRS Researcher

CD-ROM, SIRS Government Reporter. Fall 1999.

Siegel, Judy. & # 8220 ; Hope Finds its Way to the Marketplace. & # 8221 ; Jerusalem Post, 16 October 1996,

Page 6. Electric Library. Online. Internet. 25 January 2000.

Squires, Sally. & # 8220 ; Interferon Drugs Offer Hope to MS Patients ; Researchers Say Injections

Reduce the Brain Shrinking that is Common in Patients. & # 8221 ; The Washington Post,

4 May 1999. Electric Library. Online. Internet. 20 January 2000.

Talan, Jaime. & # 8220 ; New Hope for MS Patients. & # 8221 ; The Record, 26 January 1998. Reproduced

In SIRS Researcher CD-ROM, SIRS Mandarin. Fall 1999.

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